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Post Doctorate RA - Multi-omics of Health and Disease

Company: Pacific Northwest National Laboratory
Location: Richland
Posted on: November 16, 2022

Job Description:

**Overview**

The Integrative Omics Group at PNNL is seeking postdoctoral fellow to join our multi-disciplinary team with a focus on mass spectrometry-based omics analyses. The postdoc will be working across multiple cutting-edge and synergistic NIH-funded projects on human physiology and metabolism. PNNL has vibrant research programs in Lung Biology, Diabetes, Aging, Cancer, Alzheimer's Disease, Exercise Physiology, Metabolism among others. (for references, see Nakayasu et al. Cell Metabolism, 2020, DOI: 10.1016/j.cmet.2019.12.005; Clair et al., Am J Respir Crit Care Med, 2022, DOI: 10.1164/rccm.202008-3303OC; Dou et al., Cell. 2020, DOI: 10.1016/j.cell.2020.01.026; Shi et al., PNAS, 2013, DOI: 10.1073/pnas.1204366109; Fulcher et al, J Proteome Res, 2021, DOI: 10.1021/acs.jproteome.1c00049). The individual will be performing a single or a combination of deep mass spectrometry-based omics (proteomics, lipidomics, metabolomics, and/or analysis of post-translational modifications) and functional and analyses of cells, tissues, protein complexes, and biofluids to discover and probe novel mechanistic pathways that drive normal human development and dysregulations that contribute to diseases. The candidate will have the opportunity to receive technical training in the latest cutting-edge mass spectrometry applications available within PNNL's world-class Environmental Molecular Sciences Laboratory which houses over 40 top-of-the-line mass spectrometers. The center also houses other high-end resources, such as nuclear magnetic resonance, single molecule microscopy, cryo-electron microscopy, and mass cytometry.

This is a full-time, limited term employment position. The duration of this appointment is two years, with the option of extending the appointment for up to three years. Salary is commensurate with qualifications and experience but is among the most competitive of the market.

**Responsibilities**

The selected candidate is expected to 1) Conduct independent research and work on team assignments, lead manuscripts and maintain a strong overall publication record in the peer-reviewed scientific literature, 2) Interact, communicate, and problem-solve with a diverse team of multi-disciplinary research staff across PNNL, 3) Present research projects at national conferences, (4) Work safely and independently in a laboratory setting, and (5) Participate in the development of research proposals.

**Qualifications**

Minimum Qualifications:

+ Candidates must have received a PhD within the past five years (60 months) or within the next 8 months from an accredited college or university.

Preferred Qualifications:

Strong organization and communication skills are needed to work efficiently in a team environment and to effectively demonstrate project success. The ideal candidate would have a Ph.D. degree in the biological sciences, chemistry or closely related fields. Hands-on experience with chromatography (immunoaffinity, size exclusion, etc.), LC-MS for acquiring proteomics data from cells, tissues and/or biofluids, and the ability to tackling large, complex multi-omics datasets is highly desired. The candidate should have excellent "lab hands", i.e. technical expertise at the bench. Additionally, the candidate should be safety-oriented, possess excellent communication skills (oral and written), be collaborative, and have a desire to learn and develop new concepts and research techniques. The ability to critically think, problem-solve, and execute routine research tasks independently is essential.

**Hazardous Working Conditions/Environment**

The candidate will have to process samples in a biosafety level 2 laboratory.

**Additional Information**

Not applicable

**Testing Designated Position**

Not applicable

**About PNNL**

Pacific Northwest National Laboratory (PNNL) is a world-class research institution powered by a highly educated, diverse workforce committed to the values of Integrity, Creativity, Collaboration, Impact, and Courage. Every year, scores of dynamic, driven people come to PNNL to work with renowned researchers on meaningful science, innovations and outcomes for the U.S. Department of Energy and other sponsors; here is your chance to be one of them!

At PNNL, you will find an exciting research environment and excellent benefits including health insurance, flexible work schedules and telework options. PNNL is located in eastern Washington State-the dry side of Washington known for its stellar outdoor recreation and affordable cost of living. The Lab's campus is only a 45-minute flight (or -3 hour drive) from Seattle or Portland, and is serviced by the convenient PSC airport, connected to 8 major hubs.

**Commitment to Excellence, Diversity, Equity, Inclusion, and Equal Employment Opportunity**

Our laboratory is committed to a diverse and inclusive work environment dedicated to solving critical challenges in fundamental sciences, national security, and energy resiliency. We are proud to be an Equal Employment Opportunity and Affirmative Action employer. In support of this commitment, we encourage people of all racial/ethnic identities, women, veterans, and individuals with disabilities to apply for employment.

Pacific Northwest National Laboratory considers all applicants for employment without regard to race, religion, color, sex (including pregnancy, sexual orientation, and gender identity), national origin, age, disability, genetic information (including family medical history), protected veteran status, and any other status or characteristic protected by federal, state, and/or local laws.

We are committed to providing reasonable accommodations for individuals with disabilities and disabled veterans in our job application procedures and in employment. If you need assistance or an accommodation due to a disability, contact us at careers@pnnl.gov .

**Drug Free Workplace**

PNNL is committed to a drug-free workplace supported by Workplace Substance Abuse Program (WSAP) and complies with federal laws prohibiting the possession and use of illegal drugs.

**Mandatory Requirements**

Battelle requires employees to have a COVID-19 vaccine as a condition of employment, subject to accommodation. Applicants are required to disclose their vaccination status following a conditional offer of employment and must attest to being fully vaccinated with a Center for Disease Control (CDC)-approved COVID-19 vaccination, or provide documentation of need for medical or religious exemption from the COVID-19 vaccination requirement.

Please be aware that the Department of Energy (DOE) prohibits DOE employees and contractors from having any affiliation with the foreign government of a country DOE has identified as a "country of risk" without explicit approval by DOE and Battelle. If you are offered a position at PNNL and currently have any affiliation with the government of one of these countries you will be required to disclose this information and recuse yourself of that affiliation or receive approval from DOE and Battelle prior to your first day of employment.

Keywords: Pacific Northwest National Laboratory, Richland , Post Doctorate RA - Multi-omics of Health and Disease, Healthcare , Richland, Washington

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